Rabies,
Chinese Taipei
Information received on 17/07/2013 from Dr Ping-Cheng Yang, President, Agriculture Technology Research Institute, Council of Agriculture, Hsinchu City, Chinese Taipei
Summary
Report type Immediate notification
Date of start of the event 23/05/2012
Date of confirmation of the event 24/06/2013
Report date 17/07/2013
Date submitted to OIE 17/07/2013
Date event resolved 22/06/2014
Reason for notification Recurrence of a listed disease
Date of previous occurrence 08/03/1959
Manifestation of disease Sub-clinical infection
Causal agent lyssavirus
Serotype Not typed
Nature of diagnosis Laboratory (basic), Laboratory (advanced)
This event pertains to a defined zone within the country
Related reports Immediate notification (17/07/2013)
Follow-up report No. 1 (24/07/2013)
Follow-up report No. 2 (28/07/2013)
Follow-up report No. 3 (30/07/2013)
Follow-up report No. 4 (01/08/2013)
Follow-up report No. 5 (02/08/2013)
Follow-up report No. 6 (04/08/2013)
Follow-up report No. 7 (05/08/2013)
Follow-up report No. 8 (06/08/2013)
Follow-up report No. 9 (07/08/2013)
Follow-up report No. 10 (08/08/2013)
Follow-up report No. 11 (09/08/2013)
Follow-up report No. 12 (12/08/2013)
Follow-up report No. 13 (13/08/2013)
Follow-up report No. 14 (14/08/2013)
Follow-up report No. 15 (16/08/2013)
Follow-up report No. 16 (19/08/2013)
Follow-up report No. 17 (22/08/2013)
Follow-up report No. 18 (23/08/2013)
Follow-up report No. 19 (26/08/2013)
Follow-up report No. 20 (27/08/2013)
Follow-up report No. 21 (28/08/2013)
Follow-up report No. 22 (29/08/2013)
Follow-up report No. 23 (02/09/2013)
Follow-up report No. 24 (03/09/2013)
Follow-up report No. 25 (04/09/2013)
Follow-up report No. 26 (05/09/2013)
Follow-up report No. 27 (06/09/2013)
Follow-up report No. 28 (09/09/2013)
Follow-up report No. 29 (10/09/2013)
Follow-up report No. 30 (12/09/2013)
Follow-up report No. 31 (13/09/2013)
Follow-up report No. 32 (18/09/2013)
Follow-up report No. 33 (25/09/2013)
Follow-up report No. 34 (02/10/2013)
Follow-up report No. 35 (09/10/2013)
Follow-up report No. 36 (16/10/2013)
Follow-up report No. 37 (23/10/2013)
Follow-up report No. 38 (30/10/2013)
Follow-up report No. 39 (06/11/2013)
Follow-up report No. 40 (13/11/2013)
Follow-up report No. 41 (20/11/2013)
Follow-up report No. 42 (27/11/2013)
Follow-up report No. 43 (03/12/2013)
Follow-up report No. 44 (11/12/2013)
Follow-up report No. 45 (18/12/2013)
Follow-up report No. 46 (25/12/2013)
Follow-up report No. 47 (02/01/2014)
Follow-up report No. 48 (08/01/2014)
Follow-up report No. 49 (16/01/2014)
Follow-up report No. 50 (22/01/2014)
Follow-up report No. 51 (29/01/2014)
Follow-up report No. 52 (12/02/2014)
Follow-up report No. 53 (20/02/2014)
Follow-up report No. 54 (26/02/2014)
Follow-up report No. 55 (05/03/2014)
Follow-up report No. 56 (12/03/2014)
Follow-up report No. 57 (19/03/2014)
Follow-up report No. 58 (26/03/2014)
Follow-up report No. 59 (02/04/2014)
Follow-up report No. 60 (09/04/2014)
Follow-up report No. 61 (16/04/2014)
Follow-up report No. 62 (23/04/2014)
Follow-up report No. 63 (30/04/2014)
Follow-up report No. 64 (07/05/2014)
Follow-up report No. 65 (14/05/2014)
Follow-up report No. 66 (21/05/2014)
Follow-up report No. 67 (28/05/2014)
Follow-up report No. 68 (04/06/2014)
Follow-up report No. 69 (11/06/2014)
Follow-up report No. 70 (18/06/2014)
Follow-up report No. 71 (25/06/2014)
Follow-up report No. 72 (07/07/2014)
New outbreaks (3)
Outbreak 1 Lugu Township, Nantou County
Date of start of the outbreak 23/05/2012
Outbreak status Resolved (23/05/2012)
Epidemiological unit Not applicable
Affected animals
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Chinese Ferret-badger:Melogale moschata(Mustelidae) 1 1 0 0
Affected population Ferret-badger
Outbreak 2 Gukeng Township, Yunlin County
Date of start of the outbreak 25/11/2012
Outbreak status Resolved (25/11/2012)
Epidemiological unit Not applicable
Affected animals
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Chinese Ferret-badger:Melogale moschata(Mustelidae) 1 1 0 0
Affected population Ferret-badger
Outbreak 3 Yuchih Township, Nantou County
Date of start of the outbreak 29/12/2012
Outbreak status Resolved (29/12/2012)
Epidemiological unit Not applicable
Affected animals
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Chinese Ferret-badger:Melogale moschata(Mustelidae) 1 1 0 0
Affected population Ferret-badger
Summary of outbreaks Total outbreaks: 3
Total animals affected
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Chinese Ferret-badger:Melogale moschata(Mustelidae) 3 3 0 0
Outbreak statistics
Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost*
Chinese Ferret-badger:Melogale moschata(Mustelidae) ** ** 100.00% **
*Removed from the susceptible population through death, destruction and/or slaughter
**Not calculated because of missing information
Epidemiology
Source of the outbreak(s) or origin of infection
  • Unknown or inconclusive
Epidemiological comments Three dead wild ferret-badgers which were found in Nantou County in May 2012 and December 2012, and Yunlin County in November 2012 were detected by RT-PCR as suspicious rabies cases by National Taiwan University on 17 June 2013. Before the detection, National Taiwan University conducted a series of tests including necropsy, Immunohistochemistry (IHC), and RT-PCR for six months and ruled out the possibility of canine distemper and pseudo rabies. National Taiwan University then conducted RT-PCR of rabies in June 2013, and had the first positive result reported on 24 June 2013. The samples were sent to the National Laboratory on 26 June 2013 for final diagnosis. National Laboratory had then conducted RT-PCR test, direct fluorescent antibody test (not using fresh brain tissue to test) and IHC test, and found positive result by these tests. Because there was no fresh brain tissue to do the fluorescent antibody test (the gold-standard test of the OIE), in order to confirm these cases, National Laboratory had held an expert committee meeting on 16 July 2013 to discuss, and confirmed the cases as rabies. Intensified vaccination activities were conducted on the areas where these dead wild animals were collected and the monitoring is undergoing.
Control measures
Measures applied
  • Screening
  • Vaccination in response to the outbreak (s)
  • Quarantine
  • No treatment of affected animals
Measures to be applied
  • No other measures
Diagnostic test results
Laboratory name and type Species Test Test date Result
Animal Health Research Institute (National laboratory) Chinese Ferret-badger antigen (Ag) detection ELISA 09/07/2013 Positive
Animal Health Research Institute (National laboratory) Chinese Ferret-badger direct fluorescent antibody (FAT) test 17/07/2013 Positive
Animal Health Research Institute (National laboratory) Chinese Ferret-badger immunohistochemical test 09/07/2013 Positive
Animal Health Research Institute (National laboratory) Chinese Ferret-badger reverse transcription - polymerase chain reaction (RT-PCR) 09/07/2013 Positive
National Taiwan University (Private Laboratory) Chinese Ferret-badger reverse transcription - polymerase chain reaction (RT-PCR) 24/06/2013 Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.
Map of outbreak locations