Rabbit haemorrhagic disease,
Canada
Information received on 25/08/2016 from Dr Martine Dubuc, OIE Delegate for Canada, Chief Food Safety Officer Vice-President, Science Branch, Health Ministry, Canadian Food Inspection Agency, Ottawa, Canada
Summary
Report type Immediate notification
Date of start of the event 13/08/2016
Date of confirmation of the event 23/08/2016
Report date 25/08/2016
Date submitted to OIE 25/08/2016
Date event resolved 24/11/2016
Reason for notification Recurrence of a listed disease
Date of previous occurrence 30/03/2011
Manifestation of disease Clinical disease
Causal agent Calicivirus
Serotype RHDV2
Nature of diagnosis Laboratory (advanced), Necropsy
This event pertains to a defined zone within the country
Related reports Immediate notification (25/08/2016)
Follow-up report No. 1 (31/10/2016)
Follow-up report No. 2 (29/11/2016)
New outbreaks (1)
Outbreak 1 (QUE-2016-001) Mont-Joli, Bas-Saint-Laurent, Quebec
Date of start of the outbreak 03/08/2016
Outbreak status Resolved (17/11/2016)
Epidemiological unit Backyard
Affected animals
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Rabbits 18 15 13 2
Affected population QUE-2016-001 Hobby rabbit farm (companion animals).
Summary of outbreaks Total outbreaks: 1
Total animals affected
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Rabbits 18 15 13 2
Outbreak statistics
Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost*
Rabbits 83.33% 72.22% 86.67% **
*Removed from the susceptible population through death, destruction and/or slaughter
**Not calculated because of missing information
Epidemiology
Source of the outbreak(s) or origin of infection
  • Unknown or inconclusive
  • Introduction of new live animals
Epidemiological comments New rabbits were introduced from another farm recently, with high mortality observed in the following days. The Canadian Food Inspection Agency (CFIA) has initiated an investigation, in collaboration with the Ministère de l'Agriculture, des Pêcheries et de l'Alimentation du Québec in order to identify possible sources of infection. Quarantine measures have been implemented, under the authority of the CFIA. On August 23, 2016, the National Center for Foreign Animal Disease (Winnipeg, CFIA) confirmed the presence of RHDV2. A 350 base pair RT-PCR amplicon representing 3' end of VP60 gene was sequenced. The sequence showed 96.2% identity to RHDVb (or RHDV2) isolate (GenBank: KT000337.1) from São Jorge in Azores Islands.
Control measures
Measures applied
  • Screening
  • Traceability
  • Quarantine
  • Stamping out
  • Vaccination prohibited
  • No treatment of affected animals
Measures to be applied
  • Disinfection / Disinfestation
Diagnostic test results
Laboratory name and type Species Test Test date Result
National Center for Foreign Animal Disease (Winnipeg, CFIA) (National laboratory) Rabbits electron microscopy 19/08/2016 Positive
National Center for Foreign Animal Disease (Winnipeg, CFIA) (National laboratory) Rabbits nucleotide sequencing 19/08/2016 Positive
National Center for Foreign Animal Disease (Winnipeg, CFIA) (National laboratory) Rabbits nucleotide sequencing 23/08/2016 Positive
National Center for Foreign Animal Disease (Winnipeg, CFIA) (National laboratory) Rabbits reverse transcription - polymerase chain reaction (RT-PCR) 18/08/2016 Positive
Animal pathology laboratory – MAPAQ (Regional Laboratory) Rabbits histopathological examination 17/08/2016 Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.
Map of outbreak locations