Information received on 25/04/2008 from Dr Monique Eloit, Directrice générale adjointe, Direction générale de l'alimentation, Ministère de l'Agriculture et de la Pêche, PARIS Cedex 15, France
Report type Immediate notification
Date of start of the event 24/04/2008
Date of confirmation of the event 24/04/2008
Report date 24/04/2008
Date submitted to OIE 25/04/2008
Date event resolved 21/10/2008
Reason for notification Recurrence of a listed disease
Date of previous occurrence 27/02/2008
Manifestation of disease Clinical disease
Causal agent Rabies virus
Serotype RABV
Nature of diagnosis Clinical, Laboratory (advanced)
This event pertains to the whole country
Related reports Immediate notification (24/04/2008)
Follow-up report No. 1 (21/10/2008)
New outbreaks (1)
Date of start of the outbreak 24/04/2008
Outbreak status Resolved (21/10/2008)
Epidemiological unit Not applicable
Affected animals
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Dogs 2 1 1 0 0
Affected population The female dog LUGY was born in December 2007 in Gambia. She was given primary vaccination on 15 March 2008 and has a certificate of good health signed on 5 April 2008. A titration test for rabies was not made before she left Gambia for Belgium (flight Dakar-Brussels). Afterwards, the animal left Belgium on 13 April 2008 to arrive directly to the Var department (France). Her general condition was deteriorated when she arrived at the Var. The dog was examined in three veterinary clinics in the Var until the suspicion of rabies (nervous signs) was established in the third clinic. The dog died on 21 April 2008 (it was not euthanized). The head of the dog was sent to the laboratory on 22 April 2008 to search for rabies.
Summary of outbreaks Total outbreaks: 1
Total animals affected
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Dogs 2 1 1 0 0
Outbreak statistics
Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost*
Dogs 50.00% 50.00% 100.00% 50.00%
*Removed from the susceptible population through death, destruction and/or slaughter
Source of the outbreak(s) or origin of infection
  • Illegal movement of animals
Epidemiological comments There is no epidemiological link between this case of canine rabies and the one notified in February 2008. 1/ Epidemiological investigation with the owner - Departure of the dog from Gambia on 6 or 7 April 2008 - Arrival at Belgium on 7 April 2008 in the morning - Departure from Belgium and arrival at France (Var) on 13 April 2008, without stopping and without having contact with other animals - Animals having had contact with the dog: only the owner’s cat (18-year-old cat non-vaccinated against rabies). This cat, which has had no contact with other animals, will be euthanized on 25 April 2008. 2/ Test results The direct immunofluorescence test and the viral isolation are positive. An initial ELISA is negative (but this result does not brought into question the positive diagnosis of rabies). A second ELISA will be made. The typing of the virus (results on 25 April 2008) by partial gene sequencing of the nucleoprotein of the virus shows that it is a lyssavirus, genotype 1 (rabies virus), type II Africa, from West Africa and very close to the strains circulating in Guinea and Sierra Leone, suggesting a Gambian origin of this strain (no epidemiological and phylogenetic data is currently available for this country).
Control measures
Measures applied
  • Vaccination permitted (if a vaccine exists)
  • No treatment of affected animals
Measures to be applied
  • Stamping out
Diagnostic test results
Laboratory name and type Species Test Test date Result
Pasteur, Paris (National laboratory) Dogs direct immunofluorescence (DIF) test 24/04/2008 Positive
Pasteur, Paris (National laboratory) Dogs enzyme-linked immunosorbent assay (ELISA) 24/04/2008 Negative
Pasteur, Paris (National laboratory) Dogs gene sequencing 25/04/2008 Positive
Pasteur, Paris (National laboratory) Dogs pathogen isolation on cell culture 24/04/2008 Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.
Map of outbreak locations