Highly pathogenic avian influenza,
Information received on 04/12/2014 from Dr Toshiro Kawashima, CVO, Deputy Director-General, Food Safety and Consumer Affairs Bureau, Ministry of Agriculture, Forestry and Fisheries, Tokyo, Japan
Report type Follow-up report No. 3
Date of start of the event 03/11/2014
Date of confirmation of the event 13/11/2014
Report date 04/12/2014
Date submitted to OIE 04/12/2014
Date event resolved 17/02/2015
Reason for notification Recurrence of a listed disease
Date of previous occurrence 16/04/2014
Manifestation of disease Sub-clinical infection
Causal agent Highly pathogenic avian influenza virus
Serotype H5N8
Nature of diagnosis Laboratory (advanced)
This event pertains to the whole country
Related reports Immediate notification (13/11/2014)
Follow-up report No. 1 (21/11/2014)
Follow-up report No. 2 (25/11/2014)
Follow-up report No. 3 (04/12/2014)
Follow-up report No. 4 (16/12/2014)
Follow-up report No. 5 (19/12/2014)
Follow-up report No. 6 (26/12/2014)
Follow-up report No. 7 (29/12/2014)
Follow-up report No. 8 (30/12/2014)
Follow-up report No. 9 (09/01/2015)
Follow-up report No. 10 (16/01/2015)
Follow-up report No. 11 (20/01/2015)
Follow-up report No. 12 (30/01/2015)
Follow-up report No. 13 (05/02/2015)
Follow-up report No. 14 (13/02/2015)
Follow-up report No. 15 (20/02/2015)
Follow-up report No. 16 (24/04/2015)
New outbreaks (1)
Outbreak 1 Tottori-shi, Tottori
Date of start of the outbreak 18/11/2014
Outbreak status Resolved (26/11/2014)
Epidemiological unit Not applicable
Affected animals
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Anatidae (unidentified):Anatidae (incognita)(Anatidae) 1 0 0 0
Affected population A fecal sample from Anatidae (species are unidentified since only fecal samples were collected)
Summary of outbreaks Total outbreaks: 1
Total animals affected
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Anatidae (unidentified):Anatidae (incognita)(Anatidae) 1 0 0 0
Outbreak statistics
Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost*
Anatidae (unidentified):Anatidae (incognita)(Anatidae) ** ** 0.00% **
*Removed from the susceptible population through death, destruction and/or slaughter
**Not calculated because of missing information
Source of the outbreak(s) or origin of infection
  • Unknown or inconclusive
Epidemiological comments It was confirmed on 26 November 2014 that a fecal sample from Anatidae (wild birds, species unidentified) was positive for H5N8 influenza A virus. The samples had been collected on 18 November 2014 and were subject to virus isolation and RT-PCR. The confirmation tests on the pathogenicity of the virus were conducted by Tottori University and the result of gene sequencing indicated that a HA0 cleavage site of the amino acid sequence was consistent with that of highly pathogenic avian influenza virus (positive results from a fecal sample only and no clinical cases).
Control measures
Measures applied
  • Vaccination prohibited
  • No treatment of affected animals
Measures to be applied
  • No other measures
Diagnostic test results
Laboratory name and type Species Test Test date Result
Tottori University (Private Laboratory) Anatidae (unidentified) gene sequencing 26/11/2014 Positive
Tottori University (Private Laboratory) Anatidae (unidentified) haemagglutination inhibition test (HIT) 26/11/2014 Positive
Tottori University (Private Laboratory) Anatidae (unidentified) neuraminidase inhibition assay 27/11/2014 Positive
Tottori University (Private Laboratory) Anatidae (unidentified) reverse transcription - polymerase chain reaction (RT-PCR) 25/11/2014 Positive
Tottori University (Private Laboratory) Anatidae (unidentified) virus isolation 23/11/2014 Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.
Map of outbreak locations