SARS-CoV-2/COVID-19,
United States of America
Information received on 09/10/2020 from Dr Mark Davidson, Associate Administrator, USDA-APHIS, United States Department of Agriculture, Washington, United States of America
Summary
Report type Follow-up report No. 21
Date of start of the event 27/03/2020
Date of confirmation of the event 04/04/2020
Report date 09/10/2020
Date submitted to OIE 09/10/2020
Reason for notification Emerging disease
Morbidity 2 (scale 0 to 5)
Mortality 1 (scale 0 to 5)
Zoonotic impact Zoonotic potential currently unknown
Causal agent SARS-CoV-2/COVID-19
Related reports Immediate notification (06/04/2020)
Follow-up report No. 1 (17/04/2020)
Follow-up report No. 2 (22/04/2020)
Follow-up report No. 3 (29/04/2020)
Follow-up report No. 4 (02/06/2020)
Follow-up report No. 5 (03/06/2020)
Follow-up report No. 6 (10/06/2020)
Follow-up report No. 7 (25/06/2020)
Follow-up report No. 8 (02/07/2020)
Follow-up report No. 9 (09/07/2020)
Follow-up report No. 10 (17/07/2020)
Follow-up report No. 11 (23/07/2020)
Follow-up report No. 12 (30/07/2020)
Follow-up report No. 13 (05/08/2020)
Follow-up report No. 14 (13/08/2020)
Follow-up report No. 15 (20/08/2020)
Follow-up report No. 16 (27/08/2020)
Follow-up report No. 17 (02/09/2020)
Follow-up report No. 18 (10/09/2020)
Follow-up report No. 19 (24/09/2020)
Follow-up report No. 20 (02/10/2020)
Follow-up report No. 21 (09/10/2020)
Follow-up report No. 22 (16/10/2020)
Follow-up report No. 23 (30/10/2020)
Follow-up report No. 24 (06/11/2020)
Follow-up report No. 25 (16/11/2020)
New outbreaks (3)
Outbreak 1 Lee County, Lee, Alabama
Date of start of the outbreak 25/09/2020
Outbreak status Continuing (or date resolved not provided)
Epidemiological unit Other
Affected animals
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Cats 4 2 1 0 0
Affected population Pet domestic cat (Felis catus) in a residential household
Outbreak 2 Michigan, Michigan
Date of start of the outbreak 27/09/2020
Outbreak status Continuing (or date resolved not provided)
Epidemiological unit Farm
Affected animals
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
American Mink:Neovison vison(Mustelidae) 17000 2000 0 0
Affected population Domestic American Mink (Neovison vison) on a commercial farm
Outbreak 3 Wisconsin, Wisconsin
Date of start of the outbreak 30/09/2020
Outbreak status Continuing (or date resolved not provided)
Epidemiological unit Farm
Affected animals
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
American Mink:Neovison vison(Mustelidae) 14600 1800 0 0
Affected population Domestic American Mink (Neovison vison) on a commercial farm
Summary of outbreaks Total outbreaks: 3
Total animals affected
Species Susceptible Cases Deaths Killed and disposed of Slaughtered
Cats 4 2 1 0 0
American Mink:Neovison vison(Mustelidae) 31600 ** 3800 0 0
Outbreak statistics
Species Apparent morbidity rate Apparent mortality rate Apparent case fatality rate Proportion susceptible animals lost*
Cats 50.00% 25.00% 50.00% 25.00%
American Mink:Neovison vison(Mustelidae) ** 12.03% ** 12.03%
*Removed from the susceptible population through death, destruction and/or slaughter
**Not calculated because of missing information
Epidemiology
Source of the outbreak(s) or origin of infection
  • Suspected human transmission
Epidemiological comments 9 Oct 2020 Update-- Alabama (AL): A domestic cat from a known positive COVID-19 household was confirmed positive for SARS-CoV-2 at the National Veterinary Services Laboratories based upon molecular testing (PCR and sequencing). The affected cat died after exhibiting upper respiratory signs, foaming from the nose and neurologic signs, including head pressing and staggering. Necropsy results suggested a diagnosis of bacterial meningoencephalitis. The other three cats in the same household were reported to have respiratory signs and have been sampled for testing. Michigan (MI): Following increased mortality rates, domestic American Mink (Neovison vison) from a commercial premises were confirmed positive for SARS-CoV-2 at the National Veterinary Services Laboratories based upon molecular testing results (PCR and sequencing) and meeting case definition. This is the first confirmed detection of SARS-CoV-2 in mink from Michigan. Clinical signs included inappetence, respiratory difficulty, epistaxis and sudden death. The source of infection is being investigated at this time. State Officials in Michigan have quarantined the premises and are working closely with Federal One Health partners to follow up and monitor the situation. Please note: The location used for this outbreak is that of the Michigan State University Veterinary Diagnostic Laboratory (MSU VDL), where animal samples were first tested. Wisconsin (WI): Following increased mortality rates, domestic American Mink (Neovison vison) from a commercial premises were confirmed positive for SARS-CoV-2 at the National Veterinary Services Laboratories based upon molecular testing results (PCR and sequencing) and meeting case definition. This is the first confirmed detection of SARS-CoV-2 in mink from Wisconsin. Clinical signs included inappetance, respiratory difficulty, epistaxis, coffee-colored urine (black mink only) and sudden death. The affected premises reported a positive case of COVID-19 in a person that was in contact with the mink. State Officials in Wisconsin are assisting with carcass management and working closely with Federal One Health partners to follow up and monitor the situation. Please note: To protect confidentiality of any data related to human cases, the location used for this outbreak is that of the Wisconsin Veterinary Diagnostic Laboratory (WI VDL), where animal samples were first tested. Confirmed cases of SARS-CoV-2 in domestic mink from the United States have now been identified on ten commercial premises. Due to limitations with the WAHIS system, the map notation indicates disease outbreaks in wild mink, however the affected populations are domesticated American Mink (Neovison vison) from commercial premises as stated above.
Control measures
Measures applied
  • Quarantine
  • Disinfection
  • Vaccination permitted (if a vaccine exists)
  • No treatment of affected animals
Measures to be applied
  • No other measures
Diagnostic test results
Laboratory name and type Species Test Test date Result
Michigan State University Veterinary Diagnostic Laboratory (Local laboratory) American Mink real-time reverse transcriptase/polymerase chain reaction (RRT-PCR) 02/10/2020 Positive
Wisconsin Veterinary Diagnostic Laboratory (Local laboratory) American Mink real-time reverse transcriptase/polymerase chain reaction (RRT-PCR) 05/10/2020 Positive
National Veterinary Services Laboratories (National laboratory) American Mink gene sequencing 07/10/2020 Positive
National Veterinary Services Laboratories (National laboratory) American Mink real-time reverse transcriptase/polymerase chain reaction (RRT-PCR) 07/10/2020 Positive
National Veterinary Services Laboratories (National laboratory) Cats gene sequencing 06/10/2020 Positive
National Veterinary Services Laboratories (National laboratory) Cats real-time reverse transcriptase/polymerase chain reaction (RRT-PCR) 06/10/2020 Positive
National Veterinary Services Laboratories (National laboratory) Cats virus neutralisation test (VNT) 06/10/2020 Positive
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.
Map of outbreak locations