Infectious bovine rhinotracheitis/infectious pustular vulvovaginitis,
Information received on 07/01/2021 from Mr Hans Wyss, Chief Veterinary Officer, Schwarzenburgstrasse 161, Swiss Federal Veterinary Office, LIEBEFELD BERNE, Switzerland
Report type Follow-up report No. 1
Date of start of the event 09/12/2020
Date of confirmation of the event 18/12/2020
Report date 07/01/2021
Date submitted to OIE 07/01/2021
Reason for notification Recurrence of a listed disease
Date of previous occurrence 05/2015
Manifestation of disease Clinical disease
Causal agent Bovine herpesvirus (BoHV)
Nature of diagnosis Laboratory (advanced)
This event pertains to the whole country
Related reports Immediate notification (22/12/2020)
Follow-up report No. 1 (07/01/2021)
Outbreaks There are no new outbreaks in this report
Source of the outbreak(s) or origin of infection
  • Unknown or inconclusive
Epidemiological comments Testing of animals in the holding of origin as well as in four holdings of contact revealed several other positive or ambiguous reactions in the BoHV-1 ELISA. However, apart from the one cow already notified, all the other animals tested negative in the serum neutralisation test (SNT). In the BoHV-2 ELISA all these animals - the index case included - showed very strong positive reactions. Notably, the cow that tested positive in the SNT also had the highest OD values in the BoHV-2 ELISA. Brain and blood samples of the cow were further analysed and tested negative in the BoHV-1 real-time PCR. A panherpes PCR and sequencing yielded highest similarity with bovine gammaherpesvirus 6 (BoHV-6). Nasal swab and blood of another cow of the same holding also tested positive for BoHV-6. Based on the current evidence, the reported case most likely represents a singleton reactor due to unspecific or cross-reactivity in the laboratory. Nevertheless, all holdings concerned remain under movement restriction until a second round of testing confirms absence of BoHV-1. In the holding of origin of the index case testing will be performed 30 days after the slaughter of the positive animal. The other holdings will be sampled a little earlier. The serologic positive animals from 2013 to 2015 were not reported with immediate notifications, because they were classed as singleton reactors. However, those cases were reported in the 6-monthly reports. In contrast to the present case, which is associated with abortion, the animals from 2013 to 2015 were animals without clinical signs.
Control measures
Measures applied
  • Movement control inside the country
  • Disinfection
  • Vaccination prohibited
  • No treatment of affected animals
Measures to be applied
  • No other measures
Future Reporting
The event is continuing. Weekly follow-up reports will be submitted.